I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

[Steve Smith]

Glen/Nick -
>> Having said that, am I allowed to say, "Crap!  I wish you didn't have cancer!'
> Of course.  Thanks.  But just to be argumentative,
...
> I am cancer.  It's probably not true of all cancers, though.
I recently had a long conversation with a Muslim friend from Australia
who donated her bone marrow to her sister to replace hers after it was
deliberately destroyed by chemo/rad to stop *her* cancer.

This was against Islamic law but she and her family felt like they had
still done the right thing.  She is now hyper aware that her sister is a
Chimera, though she didn't have the term for it.   She believes that her
sister underwent a radical personality change after the
transplant/recovery and wants to attribute it to the "transplant".   At
first I wanted to dismiss this but on a little reflection and study,  I
am more sympathetic to her position.

The  more I read about hematopoietic cell transplant and lateral genetic
transference, the curiouser it all gets!  I feel like we need the
molecular biology equivalent of Oliver Sacks (RIP) in the house to bring
a more popular understanding to the table of this fascinating field!

I was fascinated as a child to learn about tree grafting in nut and
citrus orchards, and later organ transplants in humans, but this goes a
step further since it is roughly "systemic".   This also lead me to
reflect on birth-chimeras where multiple zygotes fuse early on to yield
a single fetus and ultimately full human organism but with a mixture of
cells with filial genomics.

I have friends who are "mirror" twins who each have a third nipple on
opposite sides of their body (slightly lower than the conventional
location).  They believed this to suggest that they had begun as
triplets and that there was such a fusion during the early embryological
process.   I didn't recognize any other chimeric properties (sometimes
evidenced by piebald skin or hair markings).

This is NOT your father's Genetics!   My father studied biology in the
late 1940s, my own molecular biology experience is roughly circa 1984,
and my daughter's PhD in molecular biology is only about 7 years old
now, yet *even her* "book larnin' " in the general field, and in
particular epigenetics is getting stale fast!

- Steve

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[Marcus G. Daniels]

Well, I assume that if my connectome could be scanned with sufficient fidelity, and stored in a computer, that it would be possible, someday, to both query my memories, but also to measure emotional responses, in silico.  Probably even start and stop consciousness.    The trick would be figuring out the interfaces, but obvious places to start would be the visual cortex, auditory centers, and various incoming nerves.    It could sort of be approaches as a machine learning problem, like is beginning to be done with replacement limbs.  

Sure there are aspects of my physical self that are slightly unique to me, but I would expect they are modularized.   The experience of running, typing, and so on.   But those things aren't me.   If anything, it would seem to be thrilling to experience other real or simulated nervous systems.  

Yes, I know, what huge waste of disk space!
Btw, what rights do the dead have to their own memories?   A whole new field of IP law!

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Steve Smith
Sent: Thursday, September 24, 2015 9:22 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Glen/Nick -
>> Having said that, am I allowed to say, "Crap!  I wish you didn't have cancer!'
> Of course.  Thanks.  But just to be argumentative,
...
> I am cancer.  It's probably not true of all cancers, though.
I recently had a long conversation with a Muslim friend from Australia who donated her bone marrow to her sister to replace hers after it was deliberately destroyed by chemo/rad to stop *her* cancer.

This was against Islamic law but she and her family felt like they had still done the right thing.  She is now hyper aware that her sister is a
Chimera, though she didn't have the term for it.   She believes that her
sister underwent a radical personality change after the
transplant/recovery and wants to attribute it to the "transplant".   At
first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.

The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!  I feel like we need the molecular biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular understanding to the table of this fascinating field!

I was fascinated as a child to learn about tree grafting in nut and citrus orchards, and later organ transplants in humans, but this goes a
step further since it is roughly "systemic".   This also lead me to
reflect on birth-chimeras where multiple zygotes fuse early on to yield a single fetus and ultimately full human organism but with a mixture of cells with filial genomics.

I have friends who are "mirror" twins who each have a third nipple on opposite sides of their body (slightly lower than the conventional location).  They believed this to suggest that they had begun as triplets and that there was such a fusion during the early embryological
process.   I didn't recognize any other chimeric properties (sometimes
evidenced by piebald skin or hair markings).

This is NOT your father's Genetics!   My father studied biology in the
late 1940s, my own molecular biology experience is roughly circa 1984, and my daughter's PhD in molecular biology is only about 7 years old now, yet *even her* "book larnin' " in the general field, and in particular epigenetics is getting stale fast!

- Steve

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[Parks, Raymond]

It would be much more convenient to store your head in a jar, a la Futurama.  And more comedic.

Ray Parks




----- Original Message -----
From: Marcus Daniels [mailto:[hidden email]]
Sent: Thursday, September 24, 2015 09:33 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [EXTERNAL] Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Well, I assume that if my connectome could be scanned with sufficient fidelity, and stored in a computer, that it would be possible, someday, to both query my memories, but also to measure emotional responses, in silico.  Probably even start and stop consciousness.    The trick would be figuring out the interfaces, but obvious places to start would be the visual cortex, auditory centers, and various incoming nerves.    It could sort of be approaches as a machine learning problem, like is beginning to be done with replacement limbs.  

Sure there are aspects of my physical self that are slightly unique to me, but I would expect they are modularized.   The experience of running, typing, and so on.   But those things aren't me.   If anything, it would seem to be thrilling to experience other real or simulated nervous systems.  

Yes, I know, what huge waste of disk space!
Btw, what rights do the dead have to their own memories?   A whole new field of IP law!

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Steve Smith
Sent: Thursday, September 24, 2015 9:22 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Glen/Nick -
>> Having said that, am I allowed to say, "Crap!  I wish you didn't have cancer!'
> Of course.  Thanks.  But just to be argumentative,
...
> I am cancer.  It's probably not true of all cancers, though.
I recently had a long conversation with a Muslim friend from Australia who donated her bone marrow to her sister to replace hers after it was deliberately destroyed by chemo/rad to stop *her* cancer.

This was against Islamic law but she and her family felt like they had still done the right thing.  She is now hyper aware that her sister is a
Chimera, though she didn't have the term for it.   She believes that her
sister underwent a radical personality change after the
transplant/recovery and wants to attribute it to the "transplant".   At
first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.

The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!  I feel like we need the molecular biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular understanding to the table of this fascinating field!

I was fascinated as a child to learn about tree grafting in nut and citrus orchards, and later organ transplants in humans, but this goes a
step further since it is roughly "systemic".   This also lead me to
reflect on birth-chimeras where multiple zygotes fuse early on to yield a single fetus and ultimately full human organism but with a mixture of cells with filial genomics.

I have friends who are "mirror" twins who each have a third nipple on opposite sides of their body (slightly lower than the conventional location).  They believed this to suggest that they had begun as triplets and that there was such a fusion during the early embryological
process.   I didn't recognize any other chimeric properties (sometimes
evidenced by piebald skin or hair markings).

This is NOT your father's Genetics!   My father studied biology in the
late 1940s, my own molecular biology experience is roughly circa 1984, and my daughter's PhD in molecular biology is only about 7 years old now, yet *even her* "book larnin' " in the general field, and in particular epigenetics is getting stale fast!

- Steve

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[Marcus G. Daniels]

Right!

http://alcor.org/AtWork/index.html

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Parks, Raymond
Sent: Thursday, September 24, 2015 9:39 AM
To: '[hidden email]' <[hidden email]>
Subject: Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

It would be much more convenient to store your head in a jar, a la Futurama.  And more comedic.

Ray Parks




----- Original Message -----
From: Marcus Daniels [mailto:[hidden email]]
Sent: Thursday, September 24, 2015 09:33 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [EXTERNAL] Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Well, I assume that if my connectome could be scanned with sufficient fidelity, and stored in a computer, that it would be possible, someday, to both query my memories, but also to measure emotional responses, in silico.  Probably even start and stop consciousness.    The trick would be figuring out the interfaces, but obvious places to start would be the visual cortex, auditory centers, and various incoming nerves.    It could sort of be approaches as a machine learning problem, like is beginning to be done with replacement limbs.  

Sure there are aspects of my physical self that are slightly unique to me, but I would expect they are modularized.   The experience of running, typing, and so on.   But those things aren't me.   If anything, it would seem to be thrilling to experience other real or simulated nervous systems.  

Yes, I know, what huge waste of disk space!
Btw, what rights do the dead have to their own memories?   A whole new field of IP law!

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Steve Smith
Sent: Thursday, September 24, 2015 9:22 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Glen/Nick -
>> Having said that, am I allowed to say, "Crap!  I wish you didn't have cancer!'
> Of course.  Thanks.  But just to be argumentative,
...
> I am cancer.  It's probably not true of all cancers, though.
I recently had a long conversation with a Muslim friend from Australia who donated her bone marrow to her sister to replace hers after it was deliberately destroyed by chemo/rad to stop *her* cancer.

This was against Islamic law but she and her family felt like they had still done the right thing.  She is now hyper aware that her sister is a
Chimera, though she didn't have the term for it.   She believes that her
sister underwent a radical personality change after the
transplant/recovery and wants to attribute it to the "transplant".   At
first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.

The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!  I feel like we need the molecular biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular understanding to the table of this fascinating field!

I was fascinated as a child to learn about tree grafting in nut and citrus orchards, and later organ transplants in humans, but this goes a
step further since it is roughly "systemic".   This also lead me to
reflect on birth-chimeras where multiple zygotes fuse early on to yield a single fetus and ultimately full human organism but with a mixture of cells with filial genomics.

I have friends who are "mirror" twins who each have a third nipple on opposite sides of their body (slightly lower than the conventional location).  They believed this to suggest that they had begun as triplets and that there was such a fusion during the early embryological
process.   I didn't recognize any other chimeric properties (sometimes
evidenced by piebald skin or hair markings).

This is NOT your father's Genetics!   My father studied biology in the
late 1940s, my own molecular biology experience is roughly circa 1984, and my daughter's PhD in molecular biology is only about 7 years old now, yet *even her* "book larnin' " in the general field, and in particular epigenetics is getting stale fast!

- Steve

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[Steve Smith]

On 9/24/15 9:44 AM, Marcus Daniels wrote:

> Right!
>
> http://alcor.org/AtWork/index.html
>
> -----Original Message-----
> From: Friam [mailto:[hidden email]] On Behalf Of Parks, Raymond
> Sent: Thursday, September 24, 2015 9:39 AM
> To: '[hidden email]' <[hidden email]>
> Subject: Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)
>
> It would be much more convenient to store your head in a jar, a la Futurama.  And more comedic.
>
> Ray Parks
>
>

Doesn't the Alcor Splash Page just *beg* for some photo-shop action?  
clip off all the heads, put them in jars on a shelf?  Or just settle
Jars down over them en-vivo like the way pear brandy bottlers sometimes
let a pear grow (into!) the bottle they are going to distribute the
brandy in?    Sortof a space-suit theme?

Ray Kurzweil will be rolling over in his memory bank one day when we
talk like this!

- Steve

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[Marcus G. Daniels]

"Ray Kurzweil will be rolling over in his memory bank one day when we talk like this!"

Don't confuse your memmove(3) and memcpy(3).    Big trouble!

Marcus

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[glen ropella]

On 09/24/2015 08:22 AM, Steve Smith wrote:
> She believes that her sister underwent a radical personality change after the transplant/recovery and wants to attribute it to the "transplant".   At first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.
>
> The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!

I have 3 words for you: Marlin Brandt Pohlman:

http://topics.oregonlive.com/tag/marlin%20pohlman/index.html
https://www.google.com/search?tbo=p&tbm=pts&hl=en&q=inassignee:%22Pohlman+Marlin+B%22&gws_rd=ssl

When they told me I had lymphoma, I immediately worried that I could become a time-machine-patent-filing-rapist.

--
⇔ glen

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[Marcus G. Daniels]

Let's assume the bad behavior has nothing to do with the "increased mental acuity".  What is the cancer drug he attributes to his discovery of time travel?   The pharmaceutical company would no doubt like to know too.

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of glen
Sent: Thursday, September 24, 2015 10:13 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

On 09/24/2015 08:22 AM, Steve Smith wrote:
> She believes that her sister underwent a radical personality change after the transplant/recovery and wants to attribute it to the "transplant".   At first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.
>
> The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!

I have 3 words for you: Marlin Brandt Pohlman:

http://topics.oregonlive.com/tag/marlin%20pohlman/index.html
https://www.google.com/search?tbo=p&tbm=pts&hl=en&q=inassignee:%22Pohlman+Marlin+B%22&gws_rd=ssl

When they told me I had lymphoma, I immediately worried that I could become a time-machine-patent-filing-rapist.

--
⇔ glen

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[gepr]

On 09/24/2015 09:54 AM, Marcus Daniels wrote:
> Let's assume the bad behavior has nothing to do with the "increased mental acuity".  What is the cancer drug he attributes to his discovery of time travel?   The pharmaceutical company would no doubt like to know too.

I don't remember the details.  But it was speculated (by one of the local dorkbot guys) to be a result of stem cell therapy.  It's typical to take a traditional therapeutic route the 1st and even 2nd round.  So, my guess would be the stem cell therapy was the 3rd round of treatment.  We build resistance against drug and chemo classes during each round, which is why they usually use different treatment each round.  And I'm ignorant about Hodgkins, which is different from mine.  But I don't know the timing, whether he filed the patent prior to the 3rd round or what.

I kinda stopped watching Portlandia.  But it's _very_ Portlandia to have a bunch of lab equipment where you try to do things like "make absinthe" ... whether or not most of these Portlanders are actually cooking up date-rape drugs or are simply curious DIY makers is a question the TV show should pursue ... falls right in line with the Shanghai Tunnel tradition here ... maybe that's not hipster-funny enough, though.

--
⇔ glen

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[Marcus G. Daniels]

Or how about (the perception of) clear thinking motivated by a recognition of mortality.   And an ugly consequence of YOLO.

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of glen
Sent: Thursday, September 24, 2015 11:05 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

On 09/24/2015 09:54 AM, Marcus Daniels wrote:
> Let's assume the bad behavior has nothing to do with the "increased mental acuity".  What is the cancer drug he attributes to his discovery of time travel?   The pharmaceutical company would no doubt like to know too.

I don't remember the details.  But it was speculated (by one of the local dorkbot guys) to be a result of stem cell therapy.  It's typical to take a traditional therapeutic route the 1st and even 2nd round.  So, my guess would be the stem cell therapy was the 3rd round of treatment.  We build resistance against drug and chemo classes during each round, which is why they usually use different treatment each round.  And I'm ignorant about Hodgkins, which is different from mine.  But I don't know the timing, whether he filed the patent prior to the 3rd round or what.

I kinda stopped watching Portlandia.  But it's _very_ Portlandia to have a bunch of lab equipment where you try to do things like "make absinthe" ... whether or not most of these Portlanders are actually cooking up date-rape drugs or are simply curious DIY makers is a question the TV show should pursue ... falls right in line with the Shanghai Tunnel tradition here ... maybe that's not hipster-funny enough, though.

--
⇔ glen

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[gepr]

On 09/24/2015 10:18 AM, Marcus Daniels wrote:
> Or how about (the perception of) clear thinking motivated by a recognition of mortality.   And an ugly consequence of YOLO.

Ha!  Nice!  I love The Dark Side of XYZ expositions.  I attended a great talk by this guy:  http://coreypein.net/  on the Dark Side of the Sharing Economy.  He walked through several of the systemic effects of things like Uber and AirBnB, how they undermine quality of life and appeal to the myopia of both the employees and customers, alike.  Reminds me of those anti-inspirational posters you turned me on to back at the Agua Fria space.

--
⇔ glen

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[Parks, Raymond]

Actually, the Futurama version reminds me more of Abby Normal - https://www.youtube.com/watch?v=yH97lImrr0Q

Oh, and poor attempts at humour are my defense against bad news - this time about Glen.  I can sympathize - this time last year I had just been told I don't have lymphoma.  Of course, what I have is, as usual, a disease of unknown origin with symptomatic treatment at best.  There's a reason that what doctors do is called "practice".

Ray Parks
Consilient Heuristician/IDART Old-Timer
V: 505-844-4024  M: 505-238-9359  P: 505-951-6084
NIPR: [hidden email]
SIPR: [hidden email] (send NIPR reminder)
JWICS: [hidden email] (send NIPR reminder)

On Sep 24, 2015, at 9:44 AM, Marcus Daniels wrote:

Right!

http://alcor.org/AtWork/index.html

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Parks, Raymond
Sent: Thursday, September 24, 2015 9:39 AM
To: '[hidden email]' <[hidden email]>
Subject: Re: [FRIAM] [EXTERNAL] Re: I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

It would be much more convenient to store your head in a jar, a la Futurama.  And more comedic.

Ray Parks




----- Original Message -----
From: Marcus Daniels [mailto:[hidden email]]
Sent: Thursday, September 24, 2015 09:33 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [EXTERNAL] Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Well, I assume that if my connectome could be scanned with sufficient fidelity, and stored in a computer, that it would be possible, someday, to both query my memories, but also to measure emotional responses, in silico.  Probably even start and stop consciousness.    The trick would be figuring out the interfaces, but obvious places to start would be the visual cortex, auditory centers, and various incoming nerves.    It could sort of be approaches as a machine learning problem, like is beginning to be done with replacement limbs.  

Sure there are aspects of my physical self that are slightly unique to me, but I would expect they are modularized.   The experience of running, typing, and so on.   But those things aren't me.   If anything, it would seem to be thrilling to experience other real or simulated nervous systems.  

Yes, I know, what huge waste of disk space!
Btw, what rights do the dead have to their own memories?   A whole new field of IP law!

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Steve Smith
Sent: Thursday, September 24, 2015 9:22 AM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

Glen/Nick -

Having said that, am I allowed to say, "Crap!  I wish you didn't have cancer!'

Of course.  Thanks.  But just to be argumentative,

...

I am cancer.  It's probably not true of all cancers, though.

I recently had a long conversation with a Muslim friend from Australia who donated her bone marrow to her sister to replace hers after it was deliberately destroyed by chemo/rad to stop *her* cancer.

This was against Islamic law but she and her family felt like they had still done the right thing.  She is now hyper aware that her sister is a
Chimera, though she didn't have the term for it.   She believes that her
sister underwent a radical personality change after the
transplant/recovery and wants to attribute it to the "transplant".   At
first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.

The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!  I feel like we need the molecular biology equivalent of Oliver Sacks (RIP) in the house to bring a more popular understanding to the table of this fascinating field!

I was fascinated as a child to learn about tree grafting in nut and citrus orchards, and later organ transplants in humans, but this goes a
step further since it is roughly "systemic".   This also lead me to
reflect on birth-chimeras where multiple zygotes fuse early on to yield a single fetus and ultimately full human organism but with a mixture of cells with filial genomics.

I have friends who are "mirror" twins who each have a third nipple on opposite sides of their body (slightly lower than the conventional location).  They believed this to suggest that they had begun as triplets and that there was such a fusion during the early embryological
process.   I didn't recognize any other chimeric properties (sometimes
evidenced by piebald skin or hair markings).

This is NOT your father's Genetics!   My father studied biology in the
late 1940s, my own molecular biology experience is roughly circa 1984, and my daughter's PhD in molecular biology is only about 7 years old now, yet *even her* "book larnin' " in the general field, and in particular epigenetics is getting stale fast!

- Steve

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[gepr]

On 09/24/2015 11:16 AM, Parks, Raymond wrote:
> this time last year I had just been told I don't have lymphoma.  Of course, what I have is, as usual, a disease of unknown origin with symptomatic treatment at best.  There's a reason that what doctors do is called "practice".

That's both better and worse, I imagine.  It's when they _think_ they know what's happening that they get really dangerous.  Interesting shift from idiographic to idiopathic!

--
⇔ glen

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[Nick Thompson]

Hi everybody.  So much here to talk about, but if I stop to talk about it, I won't make the plane on Saturday.  

Hope to pick this up quickly on The Other Side.   By the way, all higher organisms are chimeras, and we are probably all slaves to the bacteria in our gut.  

N

Nicholas S. Thompson
Emeritus Professor of Psychology and Biology
Clark University
http://home.earthlink.net/~nickthompson/naturaldesigns/

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of glen
Sent: Thursday, September 24, 2015 12:13 PM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: Re: [FRIAM] I am Cancer, hear me roar! (with segue into Chimerism and Epigenetics)

On 09/24/2015 08:22 AM, Steve Smith wrote:
> She believes that her sister underwent a radical personality change after the transplant/recovery and wants to attribute it to the "transplant".   At first I wanted to dismiss this but on a little reflection and study,  I am more sympathetic to her position.
>
> The  more I read about hematopoietic cell transplant and lateral genetic transference, the curiouser it all gets!

I have 3 words for you: Marlin Brandt Pohlman:

http://topics.oregonlive.com/tag/marlin%20pohlman/index.html
https://www.google.com/search?tbo=p&tbm=pts&hl=en&q=inassignee:%22Pohlman+Marlin+B%22&gws_rd=ssl

When they told me I had lymphoma, I immediately worried that I could become a time-machine-patent-filing-rapist.

--
⇔ glen

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[Steve Smith]

Glen -

> On 09/24/2015 08:22 AM, Steve Smith wrote:
>> She believes that her sister underwent a radical personality change
>> after the transplant/recovery and wants to attribute it to the
>> "transplant".   At first I wanted to dismiss this but on a little
>> reflection and study,  I am more sympathetic to her position.
>>
>> The  more I read about hematopoietic cell transplant and lateral
>> genetic transference, the curiouser it all gets!
>
> I have 3 words for you: Marlin Brandt Pohlman:
>
> http://topics.oregonlive.com/tag/marlin%20pohlman/index.html
> https://www.google.com/search?tbo=p&tbm=pts&hl=en&q=inassignee:%22Pohlman+Marlin+B%22&gws_rd=ssl 
>
>
> When they told me I had lymphoma, I immediately worried that I could
> become a time-machine-patent-filing-rapist.
>

I don't get it?  Are you saying you had STEM cell/bone marrow transplant
from this guy and were afraid his genome might be at fault in his bad
habits (patenting fusion/gravity/time mechanisms, buying illegal drugs
with bitcoin, and date-drug-raping women)?

- Steve




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[gepr]

On 09/24/2015 03:07 PM, Steve Smith wrote:
> I don't get it?  Are you saying you had STEM cell/bone marrow transplant from this guy and were afraid his genome might be at fault in his bad habits (patenting fusion/gravity/time mechanisms, buying illegal drugs with bitcoin, and date-drug-raping women)?

No.  I didn't have stem cell therapy at all.  The 1st couple of rounds are usually traditional chemo+drug.  My drug encourages cell death by attaching to the CD20 receptor.  No, I was just worried that destroying and regrowing yourself changes you in fundamental and unpredictable ways.  Identity is already a delusion.  And ontogenesis under heavy stress is, I think, analogous to evolution under heavy selection pressure.  You can get some pretty radical changes out of it.

I wouldn't be surprised if Pohlman had been a relatively normal guy before his 3 rounds of therapy.  Brings to my mind the Stanford Prison Experiment.

--
⇔ glen

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[Steve Smith]

Glen -
> I wouldn't be surprised if Pohlman had been a relatively normal guy
> before his 3 rounds of therapy.
Since I didn't know you BC (before cancer), I don't have any reference,
maybe Guerin or Marcus can weigh in as to whether you *used to be* "a
pretty normal guy".

After meeting you in person, I *wouldn't* be that surprised if you had
filed a patent or two around time machines...   but after meeting Renee,
I'm pretty sure the DIY date-rape thing would turn out badly for you!


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[gepr]

On 09/24/2015 03:35 PM, Steve Smith wrote:
> Since I didn't know you BC (before cancer),

Of course, you don't mean BC, you mean BT (before therapy).  It's the therapy that does it, not the cancer.

> After meeting you in person, I *wouldn't* be that surprised if you had filed a patent or two around time machines...

No way, man!  Patents are for cogs in the machine.  The patent is the contract.  You're Robert Johnson.  The patent office is the Devil.

--
⇔ glen

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[Marcus G. Daniels]

"I don't get it?  Are you saying you had STEM cell/bone marrow transplant from this guy and were afraid his genome might be at fault in his bad habits"

Hypothetically, certain protein mixes could signal to somatic cells to unspool their nucleosome (to some extent) back to the form more like a stem cell.   If that happened, the new more versatile form might also carry new errors that come with age.   From the remodeled stem cells, new cells result, but one from a blueprint with some coffee spilled on it.   Could be interesting.

Marcus

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