The secret forces that squeeze and pull life into shape
https://www.nature.com/articles/d41586-021-00018-xThe SMMRY:
https://smmry.com/https://www.nature.com/articles/d41586-021-00018-x#&SM_LENGTH=7
> Researchers have begun to define the mechanisms by which cells sense, respond to and generate forces.
>
> The researchers confirmed how this was happening by looking at the proteins that span the gaps between cells, which make contact with each other to stick cells tightly together2.
>
> His group measured the forces involved by injecting oil droplets loaded with magnetic nanoparticles into the spaces between cells.
>
> A protein called myosin II, a close cousin to the protein that makes muscle cells contract, was known to flow from the middle of each cell to its edge, back and forth, during the zipping-up process.
>
> Simple cell proliferation can also signal cells to arrange themselves properly, as researchers at the University of Cambridge, UK, discovered in embryos of the clawed frog Xenopus.
>
> In part, that's because of an excess of a fibrous meshwork called extracellular matrix around the cells, and also because the cancer cells themselves are proliferating, he says.
>
> Says Fuchs, researchers had assumed that differentiated skin cells, those with fixed identities, couldn't produce mechanical forces.
--
↙↙↙ uǝlƃ
- .... . -..-. . -. -.. -..-. .. ... -..-. .... . .-. .
FRIAM Applied Complexity Group listserv
Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam
un/subscribe
http://redfish.com/mailman/listinfo/friam_redfish.comFRIAM-COMIC
http://friam-comic.blogspot.com/archives:
http://friam.471366.n2.nabble.com/
uǝʃƃ ⊥ glen
Locked
