SAR-CoV-2 and potential drug re-purposing

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SAR-CoV-2 and potential drug re-purposing

Barry MacKichan

Our NZ daughter sent us this link and calls the paper a tour de force. They have identified 332 high confidence coronavirus and human protein interactions, among which are 67 druggable human proteins or host factors targeted by 69 existing FDA-approved drugs, drugs in clinical trials or preclinical compounds. The work of evaluating these for efficacy is under way.

https://www.biorxiv.org/content/10.1101/2020.03.22.002386v2

A reminder: this is a preprint that has not been peer-reviewed, so the usual cautions apply.

A selected sample of comments on the article:

  • Wow - open access publishing and pre-print servers sure do accelerate scientific discoveries. Who would have thought...
  • Wow! This is f-ing awesome! (This one was retweeted many times)
  • And fast!

—Barry


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