Fairness in the genetic/developmental system

classic Classic list List threaded Threaded
4 messages Options
Reply | Threaded
Open this post in threaded view
|

Fairness in the genetic/developmental system

Nick Thompson

Dear Members of the Local Congregation,

 

Today I “offered” to the group the idea that Natural Selection could not function unless the genetic/developmental system was “fair” and was properly challenged on the meaning of the term, “fair.”  With a  lot help from my friends, it became clear that all I could possibly mean was that natural selection could not proceed unless there was a correlation between parents and offspring in the possession of traits.  So “fairness” must to refer to whatever it is that has, in the history of evolution, made it possible for children to resemble their parents.   The argument was laid out in a proposal I made to a colleague for a joint paper, which, however, never was written.  I attach the proposal, an abstract of the paper I hoped we’ld write.

 

Thanks for your patience, everybody. 

 

Nick


============================================================
FRIAM Applied Complexity Group listserv
Meets Fridays 9a-11:30 at cafe at St. John's College
to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove

Gendevpapabs.doc (37K) Download Attachment
Reply | Threaded
Open this post in threaded view
|

Re: Fairness in the genetic/developmental system

David Eric Smith
Nick, hi,

The idea that it would be a consequence of selection on development, to tend to modularize the relation between genetic material and traits, is I think favorably viewed.  I mention this in reply to the boldface last sentence in your abstract.  Beanbagness of gene-trait correspondences would be one level where modularization could occur, but often it is discussed with the intent to apply it at many levels concurrently.

Two authors who are well regarded and seem to contribute more light than heat (an impressive achievement in the evolution community) are Kirschner and Gerhart.  Their particular name is Facilitated Variation, but there is overlap with old arguments of Herb Simon, though in K and G’s work, justified by very detailed and expert understanding of many particular cases from developmental biology.  You may already know these two sources:
  author = "Gerhart, John and Kirschner, Marc",
  title = "Cells, Embryos, and Evolution",
  publisher = {Wiley},
  address = {New York},
  year = “1997”

  author = "Gerhart, John and Kirschner, Marc",
  title = "The theory of facilitated variation",
  journal = PNAS,
  volume = "104",
  pages = "8582--8589",
  year = “2007”

This probably is not quite the same as your framing in terms of fairness in the input/output relation, but I will hope maybe it contributes as either useful or simply interesting good science.

All best,

Eric






> On Oct 28, 2017, at 12:40 PM, Nick Thompson <[hidden email]> wrote:
>
> Dear Members of the Local Congregation,
>  
> Today I “offered” to the group the idea that Natural Selection could not function unless the genetic/developmental system was “fair” and was properly challenged on the meaning of the term, “fair.”  With a  lot help from my friends, it became clear that all I could possibly mean was that natural selection could not proceed unless there was a correlation between parents and offspring in the possession of traits.  So “fairness” must to refer to whatever it is that has, in the history of evolution, made it possible for children to resemble their parents.   The argument was laid out in a proposal I made to a colleague for a joint paper, which, however, never was written.  I attach the proposal, an abstract of the paper I hoped we’ld write.
>  
> Thanks for your patience, everybody.  
>  
> Nick
> <Gendevpapabs.doc>============================================================
> FRIAM Applied Complexity Group listserv
> Meets Fridays 9a-11:30 at cafe at St. John's College
> to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
> FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove


============================================================
FRIAM Applied Complexity Group listserv
Meets Fridays 9a-11:30 at cafe at St. John's College
to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove
Reply | Threaded
Open this post in threaded view
|

Re: Fairness in the genetic/developmental system

Nick Thompson
Thanks, Eric, for offering some flesh for these bones.    I will try to put my hands on the references.  

I think David Wilson has also had a go at this.  

I hope you are well,

Nick

Nicholas S. Thompson
Emeritus Professor of Psychology and Biology
Clark University
http://home.earthlink.net/~nickthompson/naturaldesigns/

-----Original Message-----
From: Friam [mailto:[hidden email]] On Behalf Of Eric Smith
Sent: Friday, October 27, 2017 9:59 PM
To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>
Subject: Re: [FRIAM] Fairness in the genetic/developmental system

Nick, hi,

The idea that it would be a consequence of selection on development, to tend to modularize the relation between genetic material and traits, is I think favorably viewed.  I mention this in reply to the boldface last sentence in your abstract.  Beanbagness of gene-trait correspondences would be one level where modularization could occur, but often it is discussed with the intent to apply it at many levels concurrently.

Two authors who are well regarded and seem to contribute more light than heat (an impressive achievement in the evolution community) are Kirschner and Gerhart.  Their particular name is Facilitated Variation, but there is overlap with old arguments of Herb Simon, though in K and G’s work, justified by very detailed and expert understanding of many particular cases from developmental biology.  You may already know these two sources:
  author = "Gerhart, John and Kirschner, Marc",
  title = "Cells, Embryos, and Evolution",
  publisher = {Wiley},
  address = {New York},
  year = “1997”

  author = "Gerhart, John and Kirschner, Marc",
  title = "The theory of facilitated variation",
  journal = PNAS,
  volume = "104",
  pages = "8582--8589",
  year = “2007”

This probably is not quite the same as your framing in terms of fairness in the input/output relation, but I will hope maybe it contributes as either useful or simply interesting good science.

All best,

Eric






> On Oct 28, 2017, at 12:40 PM, Nick Thompson <[hidden email]> wrote:
>
> Dear Members of the Local Congregation,
>  
> Today I “offered” to the group the idea that Natural Selection could not function unless the genetic/developmental system was “fair” and was properly challenged on the meaning of the term, “fair.”  With a  lot help from my friends, it became clear that all I could possibly mean was that natural selection could not proceed unless there was a correlation between parents and offspring in the possession of traits.  So “fairness” must to refer to whatever it is that has, in the history of evolution, made it possible for children to resemble their parents.   The argument was laid out in a proposal I made to a colleague for a joint paper, which, however, never was written.  I attach the proposal, an abstract of the paper I hoped we’ld write.
>  
> Thanks for your patience, everybody.  
>  
> Nick
> <Gendevpapabs.doc>====================================================
> ======== FRIAM Applied Complexity Group listserv Meets Fridays
> 9a-11:30 at cafe at St. John's College to unsubscribe
> http://redfish.com/mailman/listinfo/friam_redfish.com
> FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove


============================================================
FRIAM Applied Complexity Group listserv
Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove


============================================================
FRIAM Applied Complexity Group listserv
Meets Fridays 9a-11:30 at cafe at St. John's College
to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove
Reply | Threaded
Open this post in threaded view
|

Re: Fairness in the genetic/developmental system

Nick Thompson
In reply to this post by David Eric Smith

Friammers,

 

For those of you who are following  at home, here is the actual full text of the PNAS article that Eric cited.  I found a later edition of Cells, … etc  on Amazon for a very good price. 

 

Kirschner has a new book out, but, at 139$, I am afraid it will be a while before I get to it. 

 

It really is time we academics took charge of the distribution of our own work. 

 

Nick

 

Nicholas S. Thompson

Emeritus Professor of Psychology and Biology

Clark University

http://home.earthlink.net/~nickthompson/naturaldesigns/

 

 

-----Original Message-----
From: Nick Thompson [mailto:[hidden email]]
Sent: Friday, October 27, 2017 11:05 PM
To: 'The Friday Morning Applied Complexity Coffee Group' <[hidden email]>
Subject: RE: [FRIAM] Fairness in the genetic/developmental system

 

Thanks, Eric, for offering some flesh for these bones.    I will try to put my hands on the references. 

 

I think David Wilson has also had a go at this. 

 

I hope you are well,

 

Nick

 

Nicholas S. Thompson

Emeritus Professor of Psychology and Biology Clark University http://home.earthlink.net/~nickthompson/naturaldesigns/

 

-----Original Message-----

From: Friam [[hidden email]] On Behalf Of Eric Smith

Sent: Friday, October 27, 2017 9:59 PM

To: The Friday Morning Applied Complexity Coffee Group <[hidden email]>

Subject: Re: [FRIAM] Fairness in the genetic/developmental system

 

Nick, hi,

 

The idea that it would be a consequence of selection on development, to tend to modularize the relation between genetic material and traits, is I think favorably viewed.  I mention this in reply to the boldface last sentence in your abstract.  Beanbagness of gene-trait correspondences would be one level where modularization could occur, but often it is discussed with the intent to apply it at many levels concurrently.

 

Two authors who are well regarded and seem to contribute more light than heat (an impressive achievement in the evolution community) are Kirschner and Gerhart.  Their particular name is Facilitated Variation, but there is overlap with old arguments of Herb Simon, though in K and G’s work, justified by very detailed and expert understanding of many particular cases from developmental biology.  You may already know these two sources:

  author = "Gerhart, John and Kirschner, Marc",

  title = "Cells, Embryos, and Evolution",

  publisher = {Wiley},

  address = {New York},

  year = “1997”

 

  author = "Gerhart, John and Kirschner, Marc",

  title = "The theory of facilitated variation",

  journal = PNAS,

  volume = "104",

  pages = "8582--8589",

  year = “2007”

 

This probably is not quite the same as your framing in terms of fairness in the input/output relation, but I will hope maybe it contributes as either useful or simply interesting good science.

 

All best,

 

Eric

 

 

 

 

 

 

> On Oct 28, 2017, at 12:40 PM, Nick Thompson <[hidden email]> wrote:

>

> Dear Members of the Local Congregation,

> Today I “offered” to the group the idea that Natural Selection could not function unless the genetic/developmental system was “fair” and was properly challenged on the meaning of the term, “fair.”  With a  lot help from my friends, it became clear that all I could possibly mean was that natural selection could not proceed unless there was a correlation between parents and offspring in the possession of traits.  So “fairness” must to refer to whatever it is that has, in the history of evolution, made it possible for children to resemble their parents.   The argument was laid out in a proposal I made to a colleague for a joint paper, which, however, never was written.  I attach the proposal, an abstract of the paper I hoped we’ld write.

> Thanks for your patience, everybody. 

> Nick

> <Gendevpapabs.doc>====================================================

> ======== FRIAM Applied Complexity Group listserv Meets Fridays

> 9a-11:30 at cafe at St. John's College to unsubscribe

> http://redfish.com/mailman/listinfo/friam_redfish.com

> FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove

 

 

============================================================

FRIAM Applied Complexity Group listserv

Meets Fridays 9a-11:30 at cafe at St. John's College to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com

FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove


============================================================
FRIAM Applied Complexity Group listserv
Meets Fridays 9a-11:30 at cafe at St. John's College
to unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com
FRIAM-COMIC http://friam-comic.blogspot.com/ by Dr. Strangelove