Caporale on variation mechanisms in the genome.

classic Classic list List threaded Threaded
1 message Options
Reply | Threaded
Open this post in threaded view
|

Caporale on variation mechanisms in the genome.

Nick Thompson
Dear framers,

Several weeks ago, Carl Tollander assigned me Lynn Caporale's book, Darwin in the Genome.  After some resistance, I read it cover to cover.  I have been laboring over a review of it, which concludes that Caporale is confused about somethings.  Following Kim's suggested practice,  I will put a paragraph in here as a teaser and then punt you to the URL.

A review of:
 
Caporale, Lynn H. 2003.  Darwin in the Genome: Molecular strategies in biological evolution..  New York:  McGraw-Hill
 
            Not so long ago people given to argue against the “gene-fur” idea – as in “gene-fur blue eyes” or “gene-fur altruism” would often say, as a mater of doctrine, “Genes do not code for traits; genes code for proteins”.    This distinction  undermined any idea of a mapping between the genotype and the phenotype by stressing the fact that, many many developmental and environmental interactions could and did intrude between the protein gene product and the phenotypic trait. Nowadays, as the science of genomics procedes,   certainty concerning the maping between the “genetic code” and the protein products it produces is also being undermined.   Not only do genes not reliably code for traits; they don’t even seem reliably to code for proteins, ether.  Intruding between the genetic DNA and the protein phenotype is a series of extraordinary processes that go by such names as back-copying, imprinting,  repairing, editing, proofreading, cutting, splicing, slipping, transposing, and tuning that effect the reliablity with which a particular bit of  DNA produces a particular protein product.


www.clarku.edu/faculty/nthompson/1-websitestuff/texts/caporale2.doc

I just tested it.  It should work.

Nick

Nicholas S. Thompson
Professor of Psychology and Ethology
Clark University
[hidden email]
http://home.earthlink.net/~nickthompson/
[hidden email]
-------------- next part --------------
An HTML attachment was scrubbed...
URL: /pipermail/friam_redfish.com/attachments/20050122/44b8bd4c/attachment.htm